Publications by authors named "P Rovere-Querini"
Background: Frailty, a geriatric syndrome associated with adverse outcomes, lacks a universal definition. No consensus exists on the most effective frailty scale for predicting mortality.
Methods: This prospective observational study followed community-dwelling volunteers for 6 years.
Growing evidence suggests the neurobiological mechanism upholding post-COVID-19 depression mainly relates to immune response and subsequent unresolved low-grade inflammation. Herein we exploit a broad panel of cytokines serum levels measured in COVID-19 survivors at one- and three-month since infection to predict post-COVID-19 depression. 87 COVID survivors were screened for depressive symptomatology at one- and three-month after discharge through the Beck Depression Inventory (BDI-13) and the Zung Self-Rating Depression Scale (ZSDS) at San Raffaele Hospital.
View Article and Find Full Text PDFBackground: Long-COVID symptoms remain incompletely defined due to a large heterogeneity in the populations studied, case definitions, and settings of care. The aim of this study was to assess, in patients accessing care for Long-COVID, the profile of symptoms reported, the possible clustering of symptoms and cases, the functional status compared to pre-infection, and the impact on working activity.
Methods: Multicentre cohort study with a collection of both retrospective and prospective data.
Background: Obesity and frailty are prevalent geriatric conditions that share some pathophysiological mechanisms and are associated with adverse clinical outcomes. The relationship between frailty, obesity, and polymorphism remains inadequately explored. Single nucleotide polymorphisms (SNPs) offer insights into genetic predispositions that may influence the development of both frailty and obesity.
View Article and Find Full Text PDFArticle Synopsis
- Acute sarcopenia is a rapid decline in muscle mass and function in older adults after events like illness or surgery, affecting 28% to 69% of hospitalized patients but often goes undiagnosed.
- Key factors contributing to acute sarcopenia include systemic inflammation, endocrine imbalances, and anabolic resistance, with interventions like early mobilization, resistance exercises, and nutritional support showing promise.
- Future research should focus on continuous muscle assessments, finding biomarkers, and a team approach to manage sarcopenia effectively, emphasizing the importance of early interventions to prevent long-term disability.