Publications by authors named "P Rosina"
Article Synopsis
- The study presents a new methodology to analyze the network dynamics of a highly adaptable organism, focusing on its growth and network changes under stress, like starvation and varying levels of epinephrine.
- Two innovative techniques were employed: one for quantifying growth and exploration over time, and another for assessing vein diameter and contraction patterns, revealing physiological adjustments to environmental challenges.
- Findings indicate that while starvation diminishes network volume, epinephrine maintains the volume-to-area ratio, and the fractal dimension analysis shows a decrease in network complexity under stress, highlighting a constrained adaptation strategy and laying groundwork for future bioengineering applications.
Article Synopsis
- About 20%-45% of familial melanoma cases have a genetic link, prompting a study at the University Hospital of Verona to explore this connection in patients with cutaneous melanoma.
- Out of 1,320 patients, only 35 (2.7%) were tested for genetic variants, with 11.4% found to carry pathogenic variants in critical melanoma genes like CDKN2A and MITF.
- Key predictors for genetic predisposition included a family history of pancreatic cancer, multiple melanomas, and a high number of nevi, suggesting a monogenic risk for melanoma in these cases.
Article Synopsis
- - Enteric-type adenocarcinoma of the lung (lung-ETAC) is a rare and aggressive lung cancer that resembles colorectal cancer, leading to a poor prognosis.
- - An 81-year-old man was diagnosed with lung-ETAC with a specific BRAF mutation after presenting with skin lesions; initial treatment with targeted therapies improved his condition.
- - Despite initial success, the cancer progressed six months later with new skin lesions, underscoring both the potential of targeted treatments and the challenges in managing lung-ETAC.
Background: Dermoscopic features differentiating in situ nevus-associated melanoma (NAM) versus in situ de novo melanoma (DNM) are inconclusive.
Objectives: The aim of the study was to investigate the dermoscopic features associated with in situ NAM versus DNM.
Materials & Methods: This was a retrospective observational study.
Microscopic observation correlated with chemical-mineralogical characterization was performed on pigment samples from "Abrigo del Lince" rock art site (V-IV millennium BC), in order to provide contributions to the study of prehistoric schematic art on granite in the province of Badajoz (Spain). The research objectives include the understanding of technological and cultural aspects, as well as of conservation and deterioration issues related to the pictographs. The multi-analytical approach encompasses the integration of microscopic observation, SEM-EDS analysis, micro-Raman spectroscopy, and ATR-FTIR and allowed to achieve a multispectral overview of the samples and to describe their varied composition and the alteration pattern which connects them.
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