Publications by authors named "P Rosenfeld"
Purpose: Spectral-domain OCT angiography (SD-OCTA) scans were used in an algorithm developed for swept-source OCT angiography (SS-OCTA) scans to determine if SD-OCTA scans yielded similar results for the measurement of hyperreflective foci (HRF) in intermediate age-related macular degeneration (iAMD).
Design: Retrospective study.
Participants: Forty eyes from 35 patients with iAMD.
Article Synopsis
- Central Serous Chorioretinopathy (CSC) is characterized by retinal detachments due to fluid leakage, often linked to stress, psychiatric issues, or corticosteroid use, prompting a study to investigate BALAD as a potential biomarker for CSC severity.
- The research involved a global case-control study of patients with CSC, assessing clinical characteristics, risk factors, and OCT findings in those with and without Bacillary Layer Detachment (BALAD) to better understand its implications in diagnosis and treatment.
- Results showed 37 patients with CSC and BALAD, revealing distinct clinical features on examination and OCT, compared to a control group without BALAD, suggesting significant differences in the manifestation of CSC.
Article Synopsis
- This study aimed to confirm the reliability of measuring choriocapillaris flow deficit (CCFD) within a specific macular grid and to track these measurements over time.
- Researchers utilized advanced imaging technology to gather data, excluding certain areas in the scans to accurately calculate CCFD percentages in both normal eyes and those with eye conditions.
- The findings showed that the methodology is effective for monitoring changes in CCFD, particularly in cases where drusen (eye abnormalities) resolved, demonstrating the practicality of the grid strategy for longitudinal studies.
Objective: This study evaluated the safety and efficacy of elamipretide in dry age-related macular degeneration (AMD) with noncentral geographic atrophy (GA).
Design: ReCLAIM-2 was a prospective, phase II, randomized, placebo-controlled, double-masked, multicenter trial (NCT03891875).
Subjects: Patients aged ≥55 years with ≥1 eye with dry AMD with GA were enrolled.