Publications by authors named "P Rispal"
We investigated people living with HIV (PLWH)'s exposure to COVID-19 pandemic stressors and their association with distress, psychological growth, and substance use. PLWH in the ANRS CO3 AQUIVIH-NA cohort's QuAliV study (Nouvelle Aquitaine, France) completed an adapted CAIR Lab Pandemic Impact Questionnaire (C-PIQ) and reported substance use between 9/2021 to 3/2022. We described cumulative stressor exposure (score 0-16) and explored variation by PLWH characteristics (demographic, HIV-related, risk factors, psychosocial).
View Article and Find Full Text PDFArticle Synopsis
- Researchers investigated the effect of losartan, an angiotensin receptor blocker, on 28-day mortality in hospitalized COVID-19 patients compared to usual care, due to its potential impact on angiotensin levels.
- The study was stopped early due to safety concerns, showing that adverse events and hypotension were significantly higher in the losartan group (39.8% SAEs and 30.4% hypotension) versus the control group (27.2% SAEs and 15.3% hypotension).
- There was no significant difference in 28-day mortality (6.5% for losartan vs. 5.9% for usual care), indicating that ARBs should be used cautiously in this patient population to
Article Synopsis
- A low allele burden (<20%) of the CALR driver mutation is present in 10.8% of patients with CALR-mutated myeloproliferative neoplasms (MPNs), primarily seen in essential thrombocythemia.
- Patients with this low allele burden tend to have a milder disease phenotype.
- Those with less than 20% allele burden also experience a slower progression of their condition compared to patients with a higher allele burden (≥20%).
Article Synopsis
- A study assessed the quality of life (QoL) of people living with HIV in Nouvelle Aquitaine, France, revealing that while 63.5% reported good/very good QoL, significant improvements are still needed.
- The highest QoL scores were in physical and environmental domains (both median 69), while social and psychological scores were notably lower (both median 56).
- Factors like having three or more comorbidities, experiencing HIV-related stigma, and a monthly income below €1500 were linked to poorer QoL, highlighting the need to address both health and social issues to improve outcomes for all PLWH.
Article Synopsis
- The study investigated the effects of the COVID-19 pandemic on the initiation and success of antiretroviral therapy (ART) for people diagnosed with HIV in the Aquitaine region of France, comparing cases from the pandemic period (2020-2021) to those diagnosed before (2018-2020).
- It involved adults diagnosed with HIV-1 and assessed key metrics such as the time from diagnosis to ART initiation and achieved viral suppression.
- Results showed that individuals diagnosed during the pandemic had a higher likelihood of starting therapy and achieving viral suppression than those diagnosed earlier, but the study noted fewer foreign-born individuals were diagnosed during the pandemic, suggesting potential barriers to care.