Neurovascular Hamartoma of Palate-A Rare Case Report.

Unlabelled: The oral hamartoma is a unique presentation of head and neck tumors with nonspecific etiology and atypical histopathological presentation. Oral hamartomas generally present as smooth, painless, pinkish masses, histologically comprising neural and vascular components intermingled in connective tissue stroma. The presence of a neurovascular hamartoma (NVH) within the oral cavity is truly a rare entity, scarcely reported in the literature.

Clinical Profile, Hospital Course and Outcome of Children with COVID-19.

Objectives: To describe the epidemiological and clinical characteristics and outcome of hospitalized children with COVID-19 during the initial phase of the pandemic.

Methods: This was a cross-sectional descriptive study conducted at the dedicated COVID-19 hospital of a tertiary care referral center in North India. Consecutive children aged 14 y or younger who tested positive for SARS-CoV-2 by RT-PCR from nasopharyngeal swab between 1 April 2020 and 15 July 2020 were included.

Psychological Morbidity among People in Quarantine.

 This study aimed to evaluate psychological distress of persons in quarantine and compare the same with a group of persons, who are currently in lockdown.  Forty-four persons in quarantine and 45 subjects currently in lockdown were evaluated on Depression Anxiety Stress Scale II.  About three-fourth (77.

Alcohol use disorder and risk of sensitization to environmental allergens in Sub-Continental Asian Indian males.

Alcohol is known to cause elevation of serum total IgE (tIgE). Whether it can predispose to allergic disorders, however, is not clear. To assess whether alcohol can cause sensitization to allergens, we analyzed 100 individuals with alcohol use disorder (AUD) and 50 matched healthy controls.

Designing of Stable Co-crystals of Zoledronic Acid Using Suitable Coformers.

In this present study a new co-crystals of zoledronic acid with DL-tartaric acid and nicotinamide has been developed with improved solubility. Zoledronic acid is a class III drug with poor oral bioavailability due to its poor permeability and low aqueous solubility; hence an attempt has been made to improve its solubility by co-crystallization technology. Pharmaceutical cocrystals are multi-component crystals with a stoichiometric ratio of active pharmaceutical ingredients (APIs) and cocrystal coformers (CCFs) that are assembled by noncovalent interactions such as hydrogen bonds, π-π packing, and Vander Waals forces.