Differentiation between early and late complicated Lyme borreliosis by specific IgG avidity.

Patients with early complicated forms of Lyme borreliosis had a low specific IgG avidity index and patients with late forms had a high avidity index. Naturally exposed individuals had intermediate values.

Epidemiology of Lyme disease in France: Lyme borreliosis in the region of Berry sud: a six year retrospective.

The purpose of this epidemiologic retrospective is to recognize the endemic nature of Lyme borreliosis in 'Berry', region of France. Fifty-nine cases have been reported here during the past six years (1988-1994). An erythema migrans (EM), or a late manifestation concurrent with positive ELISA-test represents the main inclusion criterion (case definition used by the CDC).