[Myocardial capillary changes and formation of the "wear complex of the hypertrophic heart].

The myocardial capillary network was experimentally studied in aortic coarctation and decoarctation. Two factors were found to play an important role in the development of the wear complex of the hypertrophic heart. These included 1) failure of the myocardial capillary proliferation rate to keep up with increases in cardiac mass and 2) lag of mitochondrial hyperplasia and myofibrillar hypertrophy.

[Dynamics of the interrelationships of functional and morphologic parameters of the left and right ventricle in coarctation and decoarctation of the ascending aorta].

The contractile and ultrastructural parameters of the left and right ventricles were studied in rabbits 3 weeks after ascending aortic coarctation by a third of the baseline diameter. In other rabbits, the same parameters were studied 1, 2, 3, and 4 weeks after recovery of the normal aortic lumen following three weeks of its narrowing. It was found that a rapid recovery of the parameters under study did not occur after decoarctation despite the fact that left ventricular overload was abolished.

[The interventricular functional-morphological correlations in chronic overloading of the primarily intact left heart in a model of experimental vasorenal hypertension].

This investigation shows the work of the heart as an integral functional system where each of the ventricles plays its own vital role, especially in the case where only one ventricle is pathologically affected. Moreover, the changes in the right heart have been carefully studied, thus showing its immediate involvement in cases of left heart hemodynamical overloading. The experiment was carried out on 178 mature rabbits with a model of vasorenal arterial hypertension based upon coarctation of the abdominal aorta just above the renal arteries.

[An assessment of the differences in the reaction of the left and right heart ventricles to a long-term rise in systemic arterial pressure in experimental renoprival arterial hypertension in rabbits].

Different parameters of the function of the left and right heart ventricles were investigated in rabbits with renoprival arterial hypertension during a period of 52 weeks from the moment of modelling the process. As a result, this process was divided into 3 stages: 1. The establishment of compensation (1-4 weeks); 2.