How to Easily Depolymerize Polyurethane Foam Wastes by Superbase Catalysts in Ionic Liquids Below 100 °C.

This study introduces a novel and sustainable approach using Ionic Liquids (ILs) as a non-innocent solvent that enhances the performance of the basic catalysts to depolymerize polyurethane foam wastes (PUFWs) through hydrolysis, alcoholysis or aminolysis under mild conditions. The system is stable, fully recoverable, and reusable. Hydrolysis of PUFWs can occur in just 2 minutes at 95-98 °C, producing a white polyol that is easily separated and reused in new polyurethane synthesis.

Earth: An Oxidative Planet with Limited Atom Resources and Rich Chemistry.

Humanity faces an unprecedented survival challenge: climate change, driven by the depletion of natural resources, excessive waste generation, and deforestation. Six out of nine planetary boundaries have been exceeded, signaling that Earth is far from a safe operating space for humanity. In this Viewpoint Article we explore three critical "atomic-molecular" challenges: Earth's limited atomic resources, its oxidative nature, and very rich chemistry.

Evaluation of the neuroprotective effect of antipsychotics by serum quantification of protein S100B.

Objective: This research delves into the intricate interplay between antipsychotic medications and neuroprotection focusing on the S100B protein, a central player in the regulation of neuroapoptotic activity.

Method: Blood samples were collected to assess serum S100B protein levels using an immunoassay of immunoelectrochemiluminescence. The first two samples were collected with a 3-month interval between each, and the third sample was obtained 6 months after the previous one.

Sustainable Synthesis of New Antioxidants from Hydroxytyrosol by Direct Biocatalytic Esterification in Ionic Liquids.

Hydroxytyrosol (HT) is a nutraceutical compound, mainly found in the fruit, leaves and waste from the olive oil industry, known for exhibiting one of the highest antioxidant activities among molecules of natural origin. To harness this bioactivity in cosmetics, pharmaceuticals and the food industry, it is essential to modify the hydrophilicity of HT to enhance its compatibility with lipid-based mixtures. This chemical modification must be carried out with high selectivity to avoid compromising its radical scavenging activity.

Virtual practice facilitation as an implementation strategy for launching opioid safety committees for quality improvement in primary care: feasibility, acceptability, and intervention fidelity.

Background: Practice facilitation (PF) is an evidence-based multicomponent in-person implementation strategy. COVID-19-related lockdowns caused many implementation initiatives to rapidly shift to virtual settings, but there is limited evidence on PF deployed exclusively using virtual meeting platforms. Our objective was to assess the feasibility and acceptability of virtual PF used in a primary care setting to implement interdisciplinary opioid safety committees (OSCs) to improve care for patients using opioid medicines for persistent pain and reduce high-dose opioid prescribing.