Publications by authors named "P R Wotton"

Article Synopsis
  • - An 18-year-old female neutered Domestic Shorthair cat was investigated for seizure-like episodes, but initial examinations and tests showed no significant issues.
  • - Diagnostic tests, including echocardiography and electrocardiography, indicated suspected ventricular pre-excitation due to an accessory pathway, despite no structural heart disease being present.
  • - Further testing was declined by the owner, and since the ECG showed no tachycardia, no antiarrhythmic treatment was initiated for the cat.
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Article Synopsis
  • She was a trailblazer in veterinary radiology, making significant contributions to the field.
  • Known for her passion for teaching, she inspired many students and professionals alike.
  • Her impact extended beyond her work as she served as a role model for aspiring veterinarians.
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Background: Currently, the pathogenesis of congestive heart failure (CHF) in cats is not fully understood.

Objective: To identify novel biomarkers for CHF in cats caused by primary cardiomyopathy, particularly related to cardiovascular-renal axis disorder and systemic inflammatory response.

Animals: Twenty-five cats in CHF caused by primary cardiomyopathy, 12 cats with preclinical cardiomyopathy, and 20 healthy controls.

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The objective of this paper was to investigate by pedigree-based genetic means the origins and inheritance of arrhythmogenic right ventricular cardiomyopathy (ARVC) in UK Boxers and assess the role of the proposed causal mutation in the gene, Striatin (STRN). All ARVC cases traced back to a small number of imported American dogs deriving from the group of Boxers studied by Harpster (1983) to define the disease, strongly suggesting that the disease is the same in the two countries. Dogs with and without the STRN mutation were found in both ARVC affected and normal Boxers showing that the mutation is not responsible for the disease.

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