Publications by authors named "P R Sinclair"

Background: Many patients diagnosed with gastro-oesophageal reflux disease (GERD) have persistent symptoms despite proton pump inhibitor (PPI) therapy.

Aims: The aim of this consensus is to provide evidence-based statements to guide clinicians caring for patients with refractory reflux-like symptoms (rRLS) or refractory GERD.

Methods: This consensus was developed by the International Working Group for the Classification of Oesophagitis.

View Article and Find Full Text PDF

Cleaning and sanitizing are of vital importance to control Listeria monocytogenes in food processing facilities. Here, we evaluated the effect of four cleaning and sanitation standard operating procedures (SSOPs; T1, T2, T3, T4) on the reduction of total aerobic mesophilic microorganisms, the occurrence of L. monocytogenes, and the microbiota composition in three tree fruit packing facilities (F1, F2, and F3) over two packing seasons (Y1 and Y2).

View Article and Find Full Text PDF
Article Synopsis
  • The audit aimed to assess and improve the completeness and accuracy of the National Joint Registry (NJR) dataset specifically for elbow arthroplasty surgeries.
  • In a two-phase approach, Phase 1 compared NJR data with NHS England Hospital Episode Statistics (HES), identifying thousands of unmatched and inaccurate records, particularly for radial head arthroplasties (RHAs).
  • Phase 2 involved collaboration among 142 NHS hospitals to correct and update records, resulting in an improved completeness of the NJR dataset from 63% to 93% and accuracy from 94% to 98%.
View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the experiences of individuals living with heart failure in Ethiopia, focusing on how it affects their health-related quality of life.
  • - Researchers used a semi-structured interview approach with 14 participants from cardiac outpatient clinics to gather and analyze data on their experiences and coping strategies.
  • - Key findings highlighted themes such as the journey of living with heart failure, common symptoms like fatigue and depression, and the significant challenges faced, including financial issues and medication access.
View Article and Find Full Text PDF