Publications by authors named "P R Saraceni"

Article Synopsis
  • The study examines the impact of two sizes of polystyrene nanoplastics (20 nm and 80 nm) on rainbow trout and gilthead seabream cell lines, finding that 20 nm nanoplastics are more toxic.
  • Cells exposed to 20 nm PS-NPs exhibited significant structural damage and signs of apoptosis over time, while 80 nm PS-NPs were less harmful.
  • The research also identified disruptions in critical biological pathways at both sublethal and lethal doses of the smaller nanoplastics, highlighting the environmental risks posed by nanoplastics in aquatic ecosystems.
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Objective: This study aimed to investigate COVID-19 spread among people experiencing homelessness (PEH), undocumented migrants (UMs), and shelter staff of homeless service sites. Another aim has been to prevent an outbreak among these populations. A San Gallicano Institute's initiative to sustain the health system in helping hard-to-reach populations, very often with no community medical care coverage.

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The NK-lysin antimicrobial peptide, first identified in mammals, possesses both antibacterial and cytotoxic activity against cancer cell lines. Homologue peptides isolated from different fish species have been examined for their functional characteristics in the last few years. In this study, a NK-lysin transcript was identified in silico from the head kidney transcriptome of the Antarctic teleost Trematomus bernacchii.

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Background: Treatment choices for patients with advanced-stage mycosis fungoides (MF) or Sézary syndrome (SS) who have failed first-line systemic therapies can be challenging, as several options are available. However, most evidence is based on observational and early phase studies due to the rarity of the disease. Mogamulizumab has recently been approved for the treatment of adult patients with MF or SS who have received at least one prior systemic therapy; it has a good tolerability profile prompting its use in combination with other agents.

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