Publications by authors named "P R Richter"

Pseudomonas aeruginosa is a hard-to-treat human pathogen for which new antimicrobial agents are urgently needed. P. aeruginosa is known for forming biofilms, a complex aggregate of bacteria embedded in a self-generated protective matrix that enhance its resistance to antibiotics and the immune system.

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The transition towards sustainable bioprocesses requires renewable feedstocks to reduce dependency on finite resources. While plant-based feedstocks offer significant potential, their complex composition poses new challenges. The microorganisms often exhibit polyauxic growth when presented with multiple carbon sources simultaneously, consuming them in a distinct order according to their carbon source preferences.

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  • Developing sensitive and selective measurement techniques for detecting trace compounds, particularly organochlorine pesticides in water, is crucial in analytical chemistry while adhering to green chemistry principles.
  • The study utilized a solid-phase microextraction (SPME) method with an innovative clay thin film sorbent coated on nickel-titanium wire, successfully extracting multiple pesticides with high efficiency and low detection limits.
  • This eco-friendly method shows potential for improving analytical practices in environmental monitoring, offering high recovery rates and reproducibility, which could positively impact public health.
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Introduction: There is an unmet need for improved detection of intracranial aneurysms (IAs) and distinction between stable and unstable (high rupture risk) IAs. Within the IA wall, synthesis and degradation of type I collagen as the main molecular constituent balance each other to maintain IA stability. We hypothesized that collagen breakdown products could serve as molecular markers for IA presence and instability.

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  • Colorectal cancer (CRC) is a significant health issue globally, being the third most common cancer and a leading cause of death, although rates have generally decreased due to increased awareness and early detection through screening.
  • The study investigated the impact of colonoscopy on CRC incidence and explored relationships with family cancer history and symptom-to-treatment timelines, revealing a significant link between colonoscopy and CRC incidence.
  • Despite overall improvements, the rising incidence of CRC in individuals under 50 highlights the need for effective screening and timely treatment, which is critical for improving outcomes.
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