Renal cell carcinoma in childhood and adolescence: a retrospective survey for prognostic factors in 22 cases.

To identify prognostic factors for renal carcinoma in young patients, a retrospective analysis was performed of 22 patients (< or = 21 years of age) with histologically verified renal cell carcinoma. Demographic, staging, and treatment variables were collected in a database, and their effect on survival was determined using Kaplan-Meier probability distribution. The median age was 15.

Pediatric desmoid tumor: retrospective analysis of 63 cases.

Purpose: This study was conducted to evaluate clinical prognostic factors predictive of the probability of recurrence of desmoid tumor (DT).

Patients And Methods: Sixty-three patients with histologically confirmed diagnosis of DT were retrospectively studied. Median age at diagnosis was 13 years.

A prospective randomized double-blind trial of bolus urokinase in the treatment of established Hickman catheter sepsis in children.

Background: The incidence of Hickman catheter sepsis is 10% to 40%, with resultant catheter loss in one third of infections. Urokinase causes dissolution of colonized intracatheter fibrin thrombi and may improve salvage.

Study Aims: To evaluate the efficacy of 12-hour-interval slow-push urokinase infusion in addition to standard antibiotic therapy in the treatment of catheter sepsis in a pediatric oncology population.

Liposarcoma in patients younger than or equal to 22 years of age.

Background: There have been few reported series of liposarcomas in patients younger than or equal to 22 years of age.

Methods: A retrospective analysis of all patients presenting with liposarcoma between 1949-1990 at Memorial Sloan-Kettering Cancer Center with age at diagnosis younger than or equal to 22 years was performed. Variables evaluated for their predictive effect on survival included anatomic location of the primary, size, and completeness of surgical resection.