Impact of the metabolic disease status in obesity and surgical weight loss on human adipose tissue bioenergetics.

Obesity is associated with insulin resistance (IR) development, a risk factor for type 2 diabetes (T2D). How mitochondrial bioenergetics, in adipose tissue (AT), differs according to distinct metabolic profiles (i.e.

Twin pregnancy during treatment with asciminib for chronic myeloid leukemia - a case report.

Managing chronic myeloid leukemia during pregnancy presents significant challenges, with limited treatment options available depending on the stage of pregnancy. All existing tyrosine kinase inhibitors are considered teratogenic, especially during the first trimester and should be avoided. In this case report, we detail the successful, unplanned dichorionic diamniotic twin pregnancy of a patient with chronic-phase myeloid leukemia previously resistant to imatinib and dasatinib who was exposed to the allosteric tyrosine kinase inhibitor asciminib during the early weeks of gestation.

The multidrug-resistant complex and phylogenetic related species: Insights into antifungal resistance mechanisms.

The rise of multidrug-resistant (MDR) fungal pathogens poses a serious global threat to human health. Of particular concern are , the complex (which includes C and var. ), and phylogenetically related species, including and .

Preventive treatment with guarana powder () mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress.

Liver damage caused by high doses of paracetamol is a global public health concern. Consequently, therapeutic strategies are being explored to prevent this damage. The bioactive compounds present in fruits have shown promise in protecting against disorders associated with paracetamol-induced liver damage.

Service robots in caring for older adults: Uncovering the current conceptual and intellectual structures and future research agenda.

Service robots have supported human activity, mainly caring for older adults, for many years. However, a new generation of service robots empowered by artificial intelligence and other novel technologies indicates an increasing use of service robots in our society. Thus, this article aims to synthesize and integrate current research on service robots in caring for older adults, identifying its conceptual and intellectual structures and future research opportunities.