Publications by authors named "P R Aldana"

The Indo-European languages are among the most widely spoken in the world, yet their early diversification remains contentious. It is widely accepted that the spread of this language family across Europe from the 5th millennium BP correlates with the expansion and diversification of steppe-related genetic ancestry from the onset of the Bronze Age. However, multiple steppe-derived populations co-existed in Europe during this period, and it remains unclear how these populations diverged and which provided the demographic channels for the ancestral forms of the Italic, Celtic, Greek, and Armenian languages.

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Article Synopsis
  • Pediatric spinal low-grade glioma (LGG-S) has no established treatment guidelines, but proton therapy (PT) could reduce toxicity and improve outcomes for these rare tumors.
  • A study examined eight pediatric patients with progressive LGG-S who received PT after initial surgery and showed promising results, including high local control (85%) and freedom from distant metastases (88%) over a 10-year follow-up.
  • Although one patient experienced malignant transformation, overall findings indicate that PT is a viable option for long-term disease control in children with unresectable LGG-S, suggesting it may be worth considering as a first-line treatment.
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Purpose: Radiation therapy (RT) causes cognitive deficits in pediatric brain tumor survivors (PBTS). Traditionally, this is measured using neuropsychological testing, which lack prediagnosis baseline and do not necessarily trigger action. This pilot project investigated a novel patient-centered outcome of scholastic performance using state-collected educational data.

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Advocacy, one of the five domains of global neurosurgery, represents a powerful avenue to influence public policy to expand access to safe, timely, and affordable neurosurgical care. In this manuscript, we characterize advocacy in global neurosurgery, describe specific neurosurgeon-led initiatives, and delineate how neurosurgeons can become involved in global neurosurgery advocacy efforts. Advocacy in global neurosurgery involves working together in organized neurosurgery with organizations focused on clinical provisions, training, and policy initiatives.

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Objective: Cerebral revascularization surgery (CRS) has been used to prevent stroke in children with sickle cell disease (SCD) and cerebral vasculopathy (e.g., moyamoya syndrome).

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