Publications by authors named "P Pysz"

Background: Tricuspid regurgitation (TR) is a common valvular disorder with limited treatment options. It occurs when tricuspid leaflet closure is prevented by dilation of the right heart or in patients with cardiac implantable rhythm devices when the transvalvular lead impedes proper closure of the valve. The management of these patients can be complicated.

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Introduction: Transcatheter closure of paravalvular leak (PVL) is still a demanding procedure due to the complex anatomy of PVL channels and risk of interference between the implanted occluder and surrounding structures. Efforts are made to improve procedural outcomes in transcatheter structural heart interventions by establishing treatment strategy in advance with the use of 3D-printed physical models based on data obtained from cardiac computed tomography (CT) studies.

Aim: In this feasibility study 3D printing of PVL models based on data recorded during transesophageal echocardiography (TEE) examinations was evaluated.

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Multifunctional devices that incorporate chemical or physical measurements combined with ways to manipulate brain tissue via drug delivery, electrical stimulation, or light for optogenetics are desired by neuroscientists. The next generation in vivo brain devices will likely utilize the extensive flexibility and rapid processing of 3D printing. This Perspective demonstrates how close we are to this reality for advanced neuroscience measurements.

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Article Synopsis
  • - Paravalvular leaks, occurring in about 15% of patients after mitral valve surgery, can lead to serious complications like heart failure, prompting the exploration of 3D-printed models to enhance interventional cardiology procedures.
  • - Researchers analyzed 3D-transesophageal echocardiography data from 8 patients to create precise models of the leaks, using advanced software for imaging and a high-quality 3D printer.
  • - The preparation and printing of these models took an average of 430.5 minutes, showing that while the process is technically possible, further studies are needed to determine if it improves the success rate of treating these leaks.
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