Publications by authors named "P Prathiba Rajalakshmi"

Background And Objective: Cerebral aneurysms occur as balloon-like outpouchings in an artery, which commonly develop at the weak curved regions and bifurcations. When aneurysms are detected, understanding the risk of rupture is of immense clinical value for better patient management. Towards this, Fluid-Structure Interaction (FSI) studies can improve our understanding of the mechanics behind aneurysm initiation, progression, and rupture.

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Article Synopsis
  • A new one-pot method was developed for creating chiral -protected amino acid substituted 1,2,4-oxadiazoles using hydroxyl amidine and a specific anhydride, promoting sustainability.
  • This simple process does not require catalysts, making it a more efficient way to synthesize these amino acids.
  • The newly synthesized compounds were tested for antibacterial activity, with one compound (4al) showing notable effectiveness against certain harmful bacteria at a minimal inhibitory concentration of 0.19 μg/mL.
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Neurologic melioidosis warrants attention in view of its rarity and lethal consequences. We performed a retrospective review of culture confirmed neurologic melioidosis reported between 2017 and 2023. Thirteen patients were identified with median age 43 years and all but three were males.

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Metallopharmaceuticals possess unique medicinal properties and have been used since ancient times. In spite of the inclusion of several metals and minerals, there is an increased interest in metallo-drugs for clinical and research purposes because of their immense therapeutic efficiency and non-toxic claim, as they are processed in addition to specific poly herbals. is one of the traditional metallopharmaceuticals used in Siddha medicine to treat various respiratory diseases and other ailments, including antidote therapy for poisonous bites.

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