Publications by authors named "P Ponsot"

Article Synopsis
  • - Pancreatic and biliary duct cancers are leading causes of acute cholangitis (AC), prompting a study comparing cancer-associated cholangitis (CAC) in 81 patients to non-cancer-associated cholangitis (NCAC) in 49 patients.
  • - While both groups showed similar clinical and biological features, CAC had higher rates of antibiotic resistance, more frequent need for multiple biliary drainages, and increased mortality at 28 days compared to NCAC.
  • - The study suggests that cholangitis linked to pancreatic or biliary cancers requires tailored antibiotic treatment and that early biliary drainage could enhance patient outcomes.
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Lateral injury of the bile duct can occur after cholecystectomy, bile duct dissection, or exploration. If direct repair is not possible, conversion to bilioenteric anastomosis can be needed with the risk of long-term bile duct infections and associated complications. We developed a new surgical technique which consist of reconstructing the bile duct with the round ligament.

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Extension of ampulloma into the lower common bile duct (CBD) is observed in up to 30% of cases. This biliary extension can prevent complete tumor resection thus is considered as a contraindication for endoscopic and even surgical ampullectomy. For ampullomas associated with a prolonged biliary extension, a pancreaticoduodenectomy is associated with a high morbidity and can be considered as an overtreatment for a benign neoplasm.

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Introduction: Although indirect evidence suggests that the incidence of pancreatic adenocarcinoma has increased in the last decade, few data are available in European countries. The aim of the present study was to update the epidemiology of pancreatic cancer in France in 2014 from the French national hospital database (Programme de Médicalisation des Systèmes d'Information).

Patients And Methods: All patients hospitalized for pancreatic cancer in France in 2014 in public or private institutions were included.

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Introduction: Pancreatic fistula (PF) are frequent after pancreatic surgical resection, and particularly after enucleation. Endoscopic treatment might be proposed for postoperative PF, but has never been evaluated after pancreatic enucleation.

Patients And Methods: From January 2000 to June 2012, 161 patients underwent pancreatic enucleation in our center.

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