Cp40-mediated complement C3 inhibition dampens inflammasome activation and inflammatory mediators storm induced by Bitis arietans venom.

The complement system plays a crucial role in various pathophysiological conditions, including snake envenomation. In this study, we investigated the effects of Bitis arietans venom on the complement system using an ex vivo human whole blood model. Our findings demonstrate that B.

Pararamosis, a Neglected Tropical Disease Induced by Caterpillar Toxins: Investigating Their Effects on Synovial Cell Inflammation.

Pararamosis, also known as Pararama-associated phalangeal periarthritis, is a neglected tropical disease primarily affecting rubber tappers in the Amazon region. It is caused by contact with the urticating hairs of the moth caterpillar, which resides in rubber plantations. The condition is marked by the thickening of the articular synovial membrane and cartilage impairment, features associated with chronic synovitis.

Metal Ion Release from Orthodontic Archwires: A Comparative Study of Biocompatibility and Corrosion Resistance.

This study investigates the release of metal ions from commonly used orthodontic archwires, specifically, stainless steel (SS), nickel-titanium (NiTi), chromium-cobalt (CrCo), and titanium-molybdenum (TMA) alloys. To simulate oral conditions, each type of wire was immersed in artificial saliva at body temperature for a four-week period. Ion release levels were analyzed through ICP-OES mass spectrometry.

Serum metabolite and metal ions profiles for breast cancer screening.

Enhancing early-stage breast cancer detection requires integrating additional screening methods with current diagnostic imaging. Omics screening, using easily collectible serum samples, could serve as an initial step. Alongside biomarker identification capabilities, omics analysis allows for a comprehensive analysis of prevalent histological types-DCIS and IDC.