Publications by authors named "P Piquet"
Idiopathic congenital abdominal aortic aneurysm (AAA) is rare, with only a few cases reported in the literature. We present a case of a 3-year-old girl with a fusiform AAA measuring 19 mm in segments 4 and 5, associated with renal artery stenosis and severe hypertension. She was treated with three antihypertensive medications.
View Article and Find Full Text PDFArticle Synopsis
- Ricin is a highly toxic substance linked to bioterrorism, and while a vaccine (RiVax™) is in development, no effective treatments currently exist for ricin poisoning.
- * Studies have shown that anti-ricin monoclonal antibodies (mAbs) show great potential for neutralizing ricin and protecting against its effects in animal models.
- * One specific mAb, RicE5, demonstrated over 90% survival in mice after ricin exposure, even when administered 6 hours or, to a lesser extent, 24 hours post-exposure, suggesting strong therapeutic potential and long-term immunity.
Ricin is a toxic protein regarded as a potential chemical weapon for bioterrorism or criminal use. In the event of a ricin incident, rapid analytical methods are essential for ricin confirmation in a diversity of matrices, from environmental to human or food samples. Mass spectrometry-based methods provide specific toxin identification but require prior enrichment by antibodies to reach trace-level detection in matrices.
View Article and Find Full Text PDFTo assess the ability of the aortic aneurysm volume (AAV), aneurysmal lumen volume (ALV), and aneurysmal thrombus volume (ATV) to predict the need for aortic reintervention when using the maximal aortic diameter as a reference. This monocentric retrospective study included 31 consecutive patients who underwent successful thoracic endovascular aortic repair (TEVAR) to treat an atheromatous thoracic aortic aneurysm. All patients underwent clinical and computed tomography angiography (CTA) for 3 years after TEVAR.
View Article and Find Full Text PDFObjective: Due to its favorable outcome regarding late morbidity and mortality, thoracic endovascular repair (TEVAR) is becoming more popular for uncomplicated type B aortic dissection (TBAD). This study aimed to compare preemptive endovascular treatment and optimal medical treatment (OMT) and OMT alone in patients presenting uncomplicated TBAD with predictors of aortic progression.
Design: Retrospective multicenter study.