Publications by authors named "P Philippe-Chomette"

Introduction: Total nephrectomies for the treatment of Wilms' tumor (WT) are more and more performed by laparoscopy, although indications for this approach following the UMBRELLA guidelines are currently very restrictive. The purpose of this study was to assess the compliance to the criteria of the UMBRELLA protocol for minimally invasive approach of WT.

Methods: This retrospective multicenter study included children operated on by laparoscopic total nephrectomy for suspected WT before 2020.

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Article Synopsis
  • Pancreatic neuroendocrine neoplasms (pNENs) are rare in children, with a study examining cases between 2011 and 2020 to understand their clinical presentation and behavior.
  • The study analyzed 15 patients, mostly adolescents, and found that a significant number had cancer predisposition syndromes, with some diagnosed through screening.
  • Results showed that patients with low-grade tumors had better survival rates, while those with high-grade or metastatic cancers faced poorer outcomes, highlighting the need for improved treatment strategies for severe cases.
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Background: A growing number of centers worldwide are preserving testicular tissue (TT) of young boys at risk of fertility loss to preserve their fertility. Data in this regard are scarce and experience sharing is essential to the optimization of the process.

Objectives: This report of our 10-year activity of pediatric fertility preservation (FP) has the objective to (1) improve knowledge regarding the feasibility, acceptability, safety, and potential usefulness of the procedure; (2) analyze the impact of chemotherapy on spermatogonia in the cryopreserved TT.

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Purpose: To confirm the overall benignity of fat-containing soft tissue tumors (STT) on a pediatric cohort and to define the clinical and imaging features that warrant a biopsy.

Methods: A retrospective monocentric study was conducted on patients aged less than 25 years consecutively referred for fat-containing STT to our Comprehensive Cancer Center between 1998 and 2022. Tumor imaging characteristics at diagnosis (US, CT, or MRI) were correlated with pathology.

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Purpose: Childhood cancer is rare, and treatment is frequently associated with long-term morbidity. Disparities in survival and long-term side effects encourage the establishment of networks to increase access to complex organ-conservative strategies, such as brachytherapy. We report our experience of an international cooperation model in childhood cancers.

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