Publications by authors named "P Pezeshkian"

Deep brain stimulation (DBS) is a neurosurgical procedure that depends on high-accuracy targeting of structures to implant electrodes within the brain. The positioning of these electrodes in the brain determines the long-term efficacy of treating diseases such as Parkinson's disease, essential tremor, or dystonia. Misplaced electrodes in DBS can lead to poor efficacy and stimulation-induced side effects.

View Article and Find Full Text PDF
Article Synopsis
  • - The case discusses a rare World Health Organization grade II ectopic meningioma found in the infraclavicular brachial plexus, causing pain but not linked to a primary malignant meningioma in the central nervous system.
  • - Upon surgical examination, a rubbery tumor was discovered on the median nerve, showing characteristics unlike typical schwannomas and confirmed as an atypical epithelioid neoplasm through histopathological studies.
  • - The authors emphasize the rarity of primary ectopic meningiomas and recommend surgery for complete tumor removal, along with radiation therapy, imaging, and genetic screening due to the tumor's unusual high-grade nature and potential complications.
View Article and Find Full Text PDF

Frame-based stereotactic localization is an important step for targeting during a surgical procedure. The motion may cause artifacts in this step reducing the accuracy of surgical targeting. While modeling of motion in real-life scenarios may be difficult, herein we analyzed the case where motion was suspected to impact the localization step.

View Article and Find Full Text PDF

Background: Efficacy in deep brain stimulation (DBS) is dependent on precise positioning of electrodes within the brain. Intraoperative fluoroscopy, computed tomography (CT), or magnetic resonance imaging are used for stereotactic intraoperative localization (StIL), but the utility of biplanar X-ray has not been evaluated in detail.

Objective: To determine if analysis of orthogonal biplanar X-rays using graphical analysis (GA), ray tracing (RT), and/or perspective projection (PP) can be utilized for StIL.

View Article and Find Full Text PDF

Background: Cerebrovascular accident (CVA) is a potentially devastating complication of deep brain stimulation (DBS) surgery. Although there are substantial data reporting the incidence and cause of hemorrhagic CVA, reports of acute ischemic infarctions during DBS implantation surgery are rare.

Objective: To present a series of 5 patients who experienced clinically significant ischemic CVA during microelectrode-guided globus pallidus internus (GPi) DBS, and evaluate the potential risk factors and mechanisms.

View Article and Find Full Text PDF