Immunogenicity profile after COVID-19 vaccination in patients with onco-hematological diseases.

Objective: To evaluate the influence of onco-hematological pathologies on seroconversion to COVID-19 vaccines, in addition to the effects of chemotherapy treatment on this response.

Methods: The present study evaluated the immunogenic response of 76 patients with onco-hematological diseases to multiple vaccine platforms compared to 25 control individuals.

Results: Our results showed positive response rates of 74.

Exploring the relationships between safety and maintenance in the cold generation process: insights from the functional resonance analysis method.

Industrial refrigeration systems typically use ammonia as a refrigerant gas, which is a toxic gas so leaks can be catastrophic. This study aimed to identify how to improve robustness in a cold generation process using the functional resonance analysis method (FRAM). A case study was conducted through interviews and direct observations to develop three FRAM models: one focusing on operation and maintenance functions; another focusing on functions related to the provision of occupational health and safety (OHS) measures; and a third overlapping the first two models.

Posterior Circulation Evaluation in Patients with Sickle Cell Anemia.

Background: The role of transcranial Doppler (TCD) ultrasonography in identifying children with sickle cell anemia (SCA) at risk for stroke is well known; however, the major studies that evaluated TCD velocities in children with SCA did not report posterior circulation evaluation data. The objective of our study was to describe the pattern of blood flow velocities in the posterior circulation of patients with SCA and to examine their relationship with findings on magnetic resonance imaging (MRI)/magnetic resonance angiography (MRA).

Methods: All adult patients with SCA followed in the outpatient clinic of our hospital were evaluated with TCD and MRI/MRA.