Publications by authors named "P Perge"
Article Synopsis
- The study investigates how local impedance (LI) changes during ablation procedures can predict the effectiveness of creating lesions in heart tissue.
- Researchers analyzed data from over 600 ablation applications, finding that successful applications had a significant and sustained drop in LI, while unsuccessful ones only showed a minor decrease.
- The results suggest that monitoring LI drop, especially within the first 4 seconds of treatment, can be a useful indicator for the likelihood of effective lesion formation in cardiac ablation.
Article Synopsis
- The study investigates the effectiveness of high-power short-duration (90 W/4 s) radiofrequency ablation for pulmonary vein isolation (PVI) in patients with atrial fibrillation, particularly looking at gaps in ablation lines that can lead to recurrences.
- Using data from 20 patients and analyzing 1,357 ablation points, the researchers identified key factors affecting the occurrence of these gaps, including interlesion distance (ILD) and generator impedance.
- The findings suggest that smaller ILDs (3.5 mm anteriorly and 4 mm posteriorly) improve the durability of PVI, indicating that adjustments in ablation techniques might be necessary compared to traditional approaches.
Effect of early catheter ablation of atrial fibrillation in patients with heart failure.
J Cardiovasc Electrophysiol
July 2024
Introduction: According to current guidelines, pulmonary vein isolation as first-line therapy should be considered for patients with atrial fibrillation (AF), however, optimal timing of the procedure is still unknown in patients with heart failure (HF). We aimed to evaluate the effect of early catheter ablation (CA) in patients with HF and left ventricular ejection fraction (LVEF) below 50%.
Methods: We analyzed data from a structured registry comprising 227 patients with paroxysmal or persistent AF and HF with LVEF < 50% who underwent radiofrequency CA between 2015 and 2022.
Atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) is predominantly attributed to pulmonary vein reconnection (PVR). Predictors of AF recurrence have been widely studied; however, data are scarce on procedural parameters that predict chronic PVR. We aimed to study PVR rates and predictors of PVR.
View Article and Find Full Text PDFBackground: High-power short-duration ablation has shown impressive efficacy and safety for pulmonary vein isolation (PVI); however, initial efficacy results with very high power short-duration ablation were discouraging. This study compared the long-term durability of PVI performed with a 90- versus 50-W power setting.
Methods: Patients were randomized 1:1 to undergo PVI with the QDOT catheter using a power setting of 90 or 50 W.