Design, Development and Evaluation of an Application based on Clinical Decision Support Systems (CDSS) for Over-The-Counter (OTC) Therapy: An Educational Interventions in Community Pharmacists.

Introduction: Mobile health (mHealth) technology-based applications provide strong medical health-care support. Applications have an important impact as tools to improve the knowledge and support the health-care team practice. In this study, an over-the-counter (OTC) therapy application was developed based on Clinical Decision Support Systems (CDSS).

Organochlorine and organophosphorus pesticides may induce brain cancer through oxidative stress.

In this study, oxidative stress was investigated as the possible mechanism of action of organochlorine pesticides (OCPs) and organophosphorus pesticides (OPPs) in primary brain tumors (PBT). The levels of seven OCP residues and enzymatic antioxidant biomarkers including erythrocyte acetylcholinesterase (AChE), superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), and paraoxonase-1 (PON-1) along with non-enzymatic oxidative biomarkers including malondialdehyde (MDA), protein carbonyl (PC), total antioxidant capacity (TAC), and nitric oxide (NO) were measured in blood samples of 73 patients with PBT and 104 healthy controls. A significant association was found between farming activities and PBT (55% of patients were engaged in farming activities while 45% had no farming experience).

A novel method based on functionalized bimodal mesoporous silica nanoparticles for efficient removal of lead aerosols pollution from air by solid-liquid gas-phase extraction.

In this study, the enrichment and novel sorbent based on functionalized bimodal mesoporous silica nanoparticles (HS-UVM and NH-UVM) was used for removal of lead aerosols pollution from air by solid liquid gas phase extraction method (SLGPE). In bench scale set up, the lead aerosols [(Pb (NO), PbO] was generated by dispersive aerosols generator system (DAGS) and removed from air by reaction loop (RL) / impinger trap (IT) in a liquid phase which was mixed with nano adsorbent in optimized pH. The effect of parameters such as, flow rate, volume of liquid phase, time stirring, temperature, concentration, pH and amount of sorbent (mg) were studied and evaluated by flame atomic absorption spectrometry (FAAS).

Serum levels of Organochlorine Pesticides and Breast Cancer Risk in Iranian Women.

Breast cancer is a multifactorial disease and its etiology is linked to multiple risk factors. There are shreds of controversial evidence that exposure to organochlorine pesticides (OCPs) are important in the etiology of breast cancer. The present study aimed to determine the circulating levels of OCPs in patients with breast tumors in Southeastern of Iran.

Organochlorine and organophosphorus pesticides and bladder cancer: A case-control study.

Background: Exposure to pesticides is associated with an increase in the incidence of cancer. We aimed to investigate the association of serum organochlorine pesticides (OCPs) and organophosphorus pesticides (OPs) levels and GSTM1/GSTT1 gene polymorphism with bladder cancer (BC).

Methods: This study was performed on 57 patients with BC and 30 controls (C).