Pituitary secretions and wake-sleep cycle.

Neurohumoral correlations of sleep are considered from three aspects: 1. Metabolism and cerebral blood circulation (CBF, EEG, endocranial pressure, cerebral temperature); 2. Neuromediators and neuropeptides (5-HT, hypnogen neuropeptides); 3.

[Clinical trial of isaxonine in alcoholic polyneuritis (author's transl)].

Forty six confirmed cases of polyneuritis were treated in a double-blind survey for 4 to 5 months. The results were evaluated in terms of clinical examinations and electrophysiological tests. There was a clearly significant difference in favour of isaxonin.

Increase in sleep related GH and Prl secretion after chronic arginine aspartate administration in man.

Arginine aspartate was administered orally (250 mg/dg/day) for one week to 5 healthy male human volunteers aged 20-35. After this period, the 24 h patterns of growth hormone (GH) and prolactin (Prl) secretion were determined by radioimmunoassay on blood samples withdrawn every 20 min and correlated with the polygraphic recordings of electroencephalogram, electromyogram and electrooculogram. the results were compared to data obtained in identical conditions with the same subjects but after a week of placebo administration.

[Electrophysiological aspects of alcoholic epilepsy (author's transl)].

Two types of neurophysiological investigations (standard EEG and polygraphic recording of sleep) were performed on a group of subjects suffering from 'alcoholic epilepsy'. Results were then compared with data from normal subjects and chronic alcoholics without epilepsy. Epileptic patterns on standard EEG are rare.