Efficacy of Cognitive Interventions in Mild Cognitive Impairment due to Alzheimer's Disease- An Open-Labelled Exploratory Analysis.

Background: Efficacy data on nonpharmacotherapy-based interventions such as cognitive retraining and mindfulness meditation on improving neuropsychological functioning in early Alzheimer's disease (AD) are sparse in Indian literature.

Objective: The objective of the study was to quantify the effect of cognitive retraining (CR) versus mindfulness training (MT) on neuropsychological test performance in patients with early AD.

Methods And Materials: We administered CR and MT strategies in two prospectively enrolled groups of individuals (N = 34) who met the criteria for mild cognitive impairment (MCI) due to AD.

Treatment of early-stage diabetic nephropathy with Siddha drug Sirupeelai Kudineer: A case series.

Diabetic Nephropathy is one of the major microvascular complications of Diabetes Mellitus, which can be detected in the earlier stage by investigating urinary microalbumin excretion levels and estimating ACR and GFR. Early treatment can delay or prevent the progression of diabetic Nephropathy. Monoherbal Siddha formulation Sirupeelai Kudineer indicated for the complications of Diabetes Mellitus is selected for this Case study.

Coconut husk-lignin derived carbon dots incorporated carrageenan based functional film for intelligent food packaging.

Carbon dots (CDs) derived from sustainable natural feed-stocks like lignin have gained wide acceptance by virtue of their renewability and promising potential in intelligent sensing applications. The precursor lignin is isolated from agro-biomass waste, coconut husk through sodium hydroxide based extraction process. CDs are synthesised from amine functionalized lignin through solvothermal process and integrated into carrageenan biopolymer matrix (1, 2 and 3 wt%).

Inorganometallic allenes [(Mn(η-CH)(CO))(μ-E)] (E = Si-Pb): bis-allylic anionic delocalisation similar to organometallic allene but differential σ-donation and π-backdonation.

The chemistry of heavy group-14 tetrel atoms is known to diverge from that of the lighter congener carbon. Here, we report the structure and bonding in inorganometallic allenes [(MnCp(CO))(μ-E)] (2E, E = Si-Pb; Cp = η-CH). These inorganometallic allenes are structurally similar to the lighter organometallic analog [(MnCp(CO))(μ-C)] (2C).

Organometallic Allene [(μ-C)(Fe(CO) ) ]: Bridging Carbon Showing Transformation from Classical Electron-Sharing Bonding to Double σ-Donor and Double π-Acceptor Ligation.

Allenes (R C=C=CR ) have been traditionally perceived to feature localized orthogonal π-bonds between the carbon centres. We have carried out quantum-mechanical studies of the organometallic allenes envisioned by the isolobal replacement of the terminal CH groups by the d Fe(CO) fragment. Our studies have identified two organometallic allenes viz.