Publications by authors named "P Papoff"
Key Clinical Message: Although the symptoms of accidental chlorine inhalation are typically mild, severe exposure can result in acute respiratory distress syndrome (ARDS). We present a case of pediatric ARDS due to chlorine exposure in which lung lavage and exogenous surfactant were successful in avoiding more invasive and costly treatments.
Abstract: Chlorine inhalation as a result of swimming pool chlorination accidents is relatively common.
Article Synopsis
- Bronchiolitis is a common viral infection in infants that can lead to serious complications, but there are currently no definitive lab tests to gauge severity, aside from demographic factors.
- This study investigated the levels of Brain-Derived Neurotrophic Factor (BDNF) in the serum of infants with bronchiolitis at discharge, finding that those with severe cases had significantly lower BDNF levels.
- The research suggests that low serum BDNF may indicate either increased use by lung cells or decreased production by those cells, highlighting the need for further investigation into this biomarker's role in disease severity.
Introduction: Although neonatal breathing patterns vary after perinatal asphyxia, whether they change during therapeutic hypothermia (TH) remains unclear. We characterized breathing patterns in infants during TH for hypoxic-ischemic encephalopathy (HIE) and normothermia after rewarming.
Methods: In seventeen spontaneously breathing infants receiving TH for HIE and in three who did not receive TH, we analyzed respiratory flow and esophageal pressure tracings for respiratory timing variables, pulmonary mechanics and respiratory effort.
Background: Our aim was to hypothesize that the COVID-19 pandemic influenced the characteristics of viral bronchiolitis by comparing the last 3 epidemics with 3 pre-COVID-19 epidemics in infants hospitalized with bronchiolitis.
Methods: We prospectively enrolled 637 consecutive infants (median age 3.0 ± 2.
Article Synopsis
- This study assesses the accuracy of a noninvasive diagnostic method for ulcerative colitis in children, using fecal calprotectin, colonic ultrasonography, and colon capsule endoscopy compared to traditional ileocolonoscopy.
- The research involved 32 pediatric patients and found that the combined noninvasive approach had a sensitivity of 95% and specificity of 100%, proving to be more tolerable than conventional procedures.
- The findings suggest that this noninvasive method is promising for diagnosing ulcerative colitis, with recommendations for further multicenter research to validate these results.