Contribution of the lateral occipital and parahippocampal cortices to pattern separation of objects and contexts.

Contextual features are integral to episodic memories; yet, we know little about context effects on pattern separation, a hippocampal function promoting orthogonalization of overlapping memory representations. Recent studies suggested that various extrahippocampal brain regions support pattern separation; however, the specific role of the parahippocampal cortex-a region involved in context representation-in pattern separation has not yet been studied. Here, we investigated the contribution of the parahippocampal cortex (specifically, the parahippocampal place area) to context reinstatement effects on mnemonic discrimination, using functional magnetic resonance imaging.

Burden of Mental Health among Patients with Inflammatory Bowel Disease-A Cross-Sectional Study from a Tertiary IBD Center in Hungary.

Inflammatory bowel diseases (IBDs) are chronic conditions that negatively affect the patient's quality of life. With the spread of the biopsychosocial model, the role of mental health in the activity and course of inflammatory bowel disease is becoming more and more recognized. Our study aimed to assess the prevalence of anxiety and depression in IBD patients in our tertiary referral center and determine the predictive factors of these mental conditions.

[Verbal Episodic Memory Test].

Background And Purpose:

How uncertain are you? Disentangling expected and unexpected uncertainty in pupil-linked brain arousal during reversal learning.

During decision making, we are continuously faced with two sources of uncertainty regarding the links between stimuli, our actions, and outcomes. On the one hand, our expectations are often probabilistic, that is, stimuli or actions yield the expected outcome only with a certain probability (expected uncertainty). On the other hand, expectations might become invalid due to sudden, unexpected changes in the environment (unexpected uncertainty).

Litmus test of rich episodic representations: Context-induced false recognition.

Context-dependent episodic memory is typically investigated using tasks in which retrieval occurs either in the reinstated context of encoding or in a completely new context. A fundamental question of episodic memory models is the level of detail in episodic memory representations containing contextual information about the encoded event. The present study examined whether memory is affected when the contexts of encoding and retrieval are highly similar but not exactly the same.