Publications by authors named "P PELLER"
Study Objectives: To determine whether adherence to continuous positive airway pressure (CPAP) in adults with uncomplicated obstructive sleep apnea differs by rural vs urban residential address.
Methods: In this prospective cohort study, we recruited adults who initiated CPAP for uncomplicated obstructive sleep apnea that was diagnosed by a physician using sleep specialist-interpreted diagnostic testing. Participants were classified as urban (community size > 100,000) or rural (community size < 100,000) by translating residential postal code into geographic census area.
Much of the extensive quantitative research linking socio-economic position (SEP) and health utilizes three common indicators: income, occupation and education. Existing survey data may enable researchers to include indicators of additional forms of capital in their analyses, permitting more nuanced consideration of the relationship between SEP and health. Our objective was to identify the breadth of survey questions related to economic, cultural, and social capital available through Statistics Canada surveys, and the extent to which those surveys also include health measures.
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- The study aimed to evaluate the effectiveness of induction chemotherapy before trimodality therapy in patients with esophageal or gastroesophageal junction adenocarcinoma, building on previous findings that suggested potential survival benefits.
- In a phase 2 trial involving 28 centers, patients were randomly assigned to receive either induction chemotherapy (Arm A) or none (Arm B) followed by standard treatment, with pathologic complete response (pathCR) as the primary measure of success.
- Results indicated that while the primary endpoint (pathCR) was not improved, patients receiving induction chemotherapy had significantly longer overall survival and disease-free survival, especially those with well/moderately differentiated tumors, prompting further investigation in future trials.
Rapid climate warming in the Arctic results in multifaceted disruption of biodiversity, faunal structure, and ecosystem health. Hypotheses have linked range expansion and emergence of parasites and diseases to accelerating warming globally but empirical studies demonstrating causality are rare. Using historical data and recent surveys as baselines, we explored climatological drivers for Arctic warming as determinants of range expansion for two temperature-dependent lungworms, Umingmakstrongylus pallikuukensis and Varestrongylus eleguneniensis, of muskoxen (Ovibos moschatus) and caribou (Rangifer tarandus), in the Canadian Arctic Archipelago from 1980 through 2017.
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