Two main types of RET/PTC oncogene, named RET/PTC-1 and 3, occur in papillary thyroid carcinomas especially in those from Belarus children after the Chernobyl nuclear accident. Several variants of RET/PTC-3 have also been found, having different break points with respect to the classical RET/PTC-3. To our knowledge, no variant of RET/PTC-1 has been described up to now.
View Article and Find Full Text PDFIn both abdominal and inguinal cryptorchism, complex morphological changes are observed with age in the undescended testis. Significant changes in the size of the seminiferous tubules are observed morphometrically; the most informative index was the surface of the tubuli and their relative volume in the total volume of the organ. The main importance in the development of cryptorchism belongs, in the authors' view, to the hormonal disturbance of the anterior lobe of hypophysis and Leydig cells which are practically absent in the undescended tests in fetuses, newborns and children of the first year of life with multiple congenital developmental abnormalities.
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