[Neuro-ophthalmological and radiological signs of Aicardi syndrome].

Described in the paper are the results of ophthalmologic, ultrasound and radiological examinations of 3 girls with the Aicardi syndrome. It was for the first time, that an expansion of the optic-nerve disk excavation was described in patients with the above syndrome; such expansion was conditioned by trans-synaptic neuron degeneration induced by lesions to optic radiation in view of prenatal of encephaloplastic processes. The changing brain white substance as projected by optic radiation was detected in all children by computer and magnetic resonance tomography.

[Humoral immune response to the retinal S-antigen in premature infants and its role in the development and course of retinopathy of prematurity].

The humoral immune response to the retinal S-antigen was studied in premature babies with active and cicatricle stages of retinopathy of the premature (RP) and in the controls (102 serum test). The presence of antibodies to the S-antigen of classes IgG and IgM was established by the enzyme multiplied analysis and by an authors' developed test-system. A definite specific humoral response to the S-antigen correlated with the nature of the course and prognosis of the disease was found in 71% of cases.

[Efficiency of detection and preventive treatment of retinopathy in premature neonates].

A total of 580 preterm babies born weighing 540-2500 g at terms less than 35 weeks were examined. The mean incidence of neonatal retinopathy under standard conditions of care in Moscow is 26%. The incidence of disease depends on body weight at birth and term of gestation.