Publications by authors named "P P Mainenti"

Presented here is a case report of a 77-year-old woman affected by rheumatoid arthritis who underwent breast-conserving surgery followed by radiation therapy (RT) for left-breast cancer and developed bronchiolitis obliterans organizing pneumonia (BOOP) after RT and during a COVID-19 vaccination campaign. BOOP incidence is an uncommon morbidity after breast RT (1.2%-2.

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Amyotrophic lateral sclerosis (ALS) is a neuromuscular progressive disorder characterized by limb and bulbar muscle wasting and weakness. A total of 30% of patients present a bulbar onset, while 70% have a spinal outbreak. Respiratory involvement represents one of the worst prognostic factors, and its early identification is fundamental for the early starting of non-invasive ventilation and for the stratification of patients.

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Endometrial cancer (EC) is intricately linked to obesity and diabetes, which are widespread risk factors. Medical imaging, especially magnetic resonance imaging (MRI), plays a major role in EC assessment, particularly for disease staging. However, the diagnostic performance of MRI exhibits variability in the detection of clinically relevant prognostic factors (e.

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Article Synopsis
  • The study aimed to create and validate a predictive model for placental accreta spectrum (PAS) in patients with placenta previa (PP) by combining clinical risk factors with ultrasound (US) and MRI signs.
  • Researchers analyzed data from 171 patients, identifying key predictors of PAS including maternal smoking, cesarean section history, and specific imaging signs from US and MRI.
  • A nomogram was developed with a strong diagnostic performance, achieving 91% sensitivity and 88% specificity in predicting PAS, indicating that MRI provides more valuable information than US alone.
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Article Synopsis
  • The study aimed to evaluate various manual segmentation methods of placenta MRI images to predict Placenta Accreta Spectrum (PAS) disorders in patients with placenta previa using machine learning radiomics analysis.
  • A total of 64 patients underwent MRI, with different segmentation techniques applied to identify areas of interest in the placenta and surrounding tissues, followed by a rigorous validation process to find the most effective method for predicting PAS.
  • Results indicated that the segmentation method focusing on the retroplacental myometrium yielded the highest prediction accuracy for PAS, suggesting its significance in developing predictive models in clinical settings.
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