Publications by authors named "P P M M Geusens"
Article Synopsis
- Abdominal aortic calcification (AAC) was found in 27.6% of patients attending a Fracture Liaison Service, with varying levels of severity among them.
- The study indicated that age, body mass index (BMI), smoking, and history of cardiovascular disease (CVD) were risk factors for AAC, while the location of fractures and bone mineral density (BMD) were not related to AAC levels.
- In patients without CVD, prevalent vertebral fractures were linked to the presence of AAC but not to its severity, suggesting the complexity of factors influencing AAC in fracture patients.
Article Synopsis
- * Researchers studied a Caucasian family with a history of AFFs and identified a rare genetic variant in the LOXL4 gene that may be associated with increased susceptibility to these fractures.
- * The LOXL4 gene is involved in collagen production, and the variant may disrupt collagen metabolism, leading to microdamage in bones and poor healing, as indicated by tests on cells from affected individuals.
The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture.
Curr Osteoporos Rep
December 2024
Purpose Of Review: We review the literature about patients 50 years and older with a recent clinical fracture for the presence of skeletal and extra-skeletal risks, their perspectives of imminent subsequent fracture, falls, mortality, and other risks, and on the role of the fracture liaison service (FLS) for timely secondary fracture prevention.
Recent Findings: Patients with a recent clinical fracture present with heterogeneous patterns of bone-, fall-, and comorbidity-related risks. Short-term perspectives include bone loss, increased risk of fractures, falls, and mortality, and a decrease in physical performance and quality of life.
Type 2 diabetes (T2D) is a prevalent disease and has been associated with an increased fracture risk despite normal or even higher areal BMD. The aim of this study was to estimate the association between glucose metabolism status (GMS) and measurements of glycemic control with HRpQCT parameters of bone microarchitecture and strength. Participants of the Maastricht study who underwent an HRpQCT scan at the distal radius and tibia were included.
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