Publications by authors named "P P L Low"

Background: Intraoperative molecular imaging (IMI) uses a cancer-targeted fluorescent agent injected into patients to localize tumor nodules. Pafolacianine is a folate receptor (FR)-targeted near-infrared fluorescent probe. Almost 10% of patients have false negative fluorescence findings intraoperatively.

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Background: Avoidant/restrictive food intake disorder (ARFID) may result in significant medical sequelae. Compared to youth with eating disorders like anorexia nervosa (AN), youth with ARFID tend to be younger and are more likely to be male. We aim to describe sex differences in clinical characteristics of youth hospitalized for medical complications of ARFID and compare their characteristics with youth hospitalized for anorexia nervosa.

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  • The study aimed to identify predicting factors and the frequency of phenoconversion from sporadic adult-onset ataxia (SAOA) to multiple system atrophy (MSA) by reviewing Mayo Clinic patient data from 1998 to 2018.
  • Out of 169 ataxia patients, 60 (35.5%) transitioned to MSA, with notable clinical features like early autonomic symptoms, stridor, and dream enactment behavior observed in these patients.
  • Imaging and autonomic testing revealed significant differences, such as pontine atrophy and abnormal blood pressure responses, indicating that specific clinical and testing features can help identify individuals likely to phenoconvert to MSA.
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  • The study analyzed data from 8006 early adolescents to assess how different types of screen time relate to substance use experimentation over one year.
  • Increased overall screen time, especially on social media, texting, and video chatting, was linked to higher likelihoods of trying substances like alcohol, nicotine, and cannabis.
  • The findings suggest that digital interactions may drive early adolescent substance use, prompting the need for further research to understand these connections better and develop effective interventions.
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Achieving bone union remains a significant clinical dilemma. The use of osteoinductive agents, specifically bone morphogenetic proteins (BMPs), has gained wide attention. However, multiple side effects, including increased incidence of cancer, have renewed interest in investigating alternatives that provide safer, yet effective bone regeneration.

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