[Bronchial hyperreactivity to the inhalation of hypo- and hyperosmolar aerosols and its correction by halotherapy].

18 bronchial asthma (BA) patients (12 with mild and 6 with moderate disease) were examined before and after halotherapy (HT) for airways reactivity using provocative tests with ultrasonic inhalations of purified water (UIPW) and hypertonic salt solution (HSS). Bronchial hyperreactivity (BHR) to UIPW and HSS before treatment occurred in 13 and 11 patients (72 and 69%, respectively). HT reduced BHR in 2/3 and 1/2 of the patients, respectively.

[Development of chronic bronchitis and possibilities of objective evaluation of its premorbid states].

A total of 163 patients with prebronchitis underwent clinical, laboratory and functional examinations from the standpoint of revealing and assessment of risk factors. Based on the data obtained the etiopathogenetic variants of the formation of chronic bronchitis (prebronchitis) were established: exogenous, endogenous and combined. The characteristic features of the variants were defined from the point of view of clinical, immunological and functional studies.

[Isocapnic cold air provocation in healthy probands].

To study the physiological response to cold air challenge, the "flow-volume-loop" method was used. Fifty-one healthies (31 males and 20 females, mean age 30 +/- 9 years) served as the subjects. Measurements were done before and subsequently 5 and 30 min after challenge.