Defining methods to improve eSource site start-up practices.

Background: eSource software that transfers patient electronic health record data into a clinical trial electronic case report form holds promise for increasing data quality while reducing data collection, monitoring and source document verification costs. Integrating eSource into multicenter clinical trial start-up procedures could facilitate the use of eSource technologies in clinical trials.

Methods: We conducted a qualitative integrative analysis to identify eSource site start-up key steps, challenges that might occur in executing those steps, and potential solutions to those challenges.

Improving eSource Site Start-Up Practices.

Background: eSource software that copies patient electronic health record data into a clinical trial electronic case report form holds promise for increasing data quality while reducing data collection, monitoring and source document verification costs. Integrating eSource into multicenter clinical trial start-up procedures could facilitate the use of eSource technologies in clinical trials.

Methods: We conducted a qualitative integrative analysis to identify eSource site start-up key steps, challenges that might occur in executing those steps, and potential solutions to those challenges.

The TRAC-PS dual radius total knee arthroplasty : Disappointing medium and long terms results.

The TRAC prosthesis is a dual radius, mobile bearing, posterior stabilized prosthesis, to increase stability by optimizing contact area and control wear using a mobile polyethylene. Between February 1995 and January 2000, a single surgeon performed a continuous series of 85 TRAC-PS TKAs in 85 patients at the University Hospital Brussels. A retrospective review on patient charts was performed.

The design features of cemented femoral hip implants.

We undertook a review of the literature relating to the two basic stem designs in use in cemented hip replacement, namely loaded tapers or force-closed femoral stems, and the composite beam or shape-closed designs. The associated stem fixation theory as understood from in vitro studies and finite element modelling were examined with reference to the survivorship results for each of the concepts of fixation. It is clear that both design principles are capable of producing successful long-term results, providing that their specific requirements of stem metallurgy, shape and surface finish, preparation of the bone and handling of the cement are observed.

Is acute compartment syndrome avoidable?

Complete absence of acute compartment syndrome was observed in a consecutive series of 966 tibial fractures in African patients of diverse ethnic groups, reviewed retrospectively at our institution. Considering the incidences reported in the literature, we should have experienced between 22 and 86 cases of acute compartment syndrome. The purpose of this prospective study was to confirm these findings and at the same time to look for possible explanations for this unexpected observation.