A Methodological Framework for Descriptive Phenomenological Research.

Background: Descriptive phenomenological research is crucial in nursing for understanding individuals' experiences, perceptions, and relationships, which are essential for person-centered healthcare. However, a common critique is that researchers often use phenomenological methods without fully comprehending their historical and philosophical foundations. Existing literature highlights discrepancies in the application of phenomenological principles by nurse researchers, particularly in their presentation of philosophical underpinnings and methodological details.

Comparative Evaluation of the Effectiveness of Rotary and Reciprocating Single File Systems on Postoperative Pain After Biomechanical Preparation in Patients With Chronic Apical Periodontitis: A Randomized Clinical Trial.

Background and objective Postoperative pain after biomechanical preparation of root canals can be equally distressing to the patient as well as the dentist and can mold the patient's attitude and trust for future dental procedures. This randomized clinical trial aimed to evaluate the effectiveness of rotary and reciprocating single-file systems on postoperative pain after biomechanical preparation in patients with chronic apical periodontitis. Materials and methods In this randomized clinical trial (CTRI Reg No-CTRI/2021/04/032841), 94 patients with chronic apical periodontitis in single straight-rooted teeth were divided equally into two groups, according to a standardized protocol.

A Study on Dysmenorrhea and Its Self-Care Behaviors Among Women of Reproductive Age in Tiruvallur District, Tamil Nadu.

Introduction:  Menstrual cramps, which can be categorized as primary or secondary depending on the etiology, are a painful feature of dysmenorrhea. Researchers from throughout the country found that self-care practices for dysmenorrhea included reducing physical activity, adjusting diet, medications, or treatments, adopting alternative therapies, recording symptom clusters of discomforts, and expressing feelings.  Methodology: There were 246 women in the reproductive age range who took part in this study.

Spatial attention-based CSR-Unet framework for subdural and epidural hemorrhage segmentation and classification using CT images.

Background: Automatic diagnosis and brain hemorrhage segmentation in Computed Tomography (CT) may be helpful in assisting the neurosurgeon in developing treatment plans that improve the patient's chances of survival. Because medical segmentation of images is important and performing operations manually is challenging, many automated algorithms have been developed for this purpose, primarily focusing on certain image modalities. Whenever a blood vessel bursts, a dangerous medical condition known as intracranial hemorrhage (ICH) occurs.

Novel PPAR-γ agonists as potential neuroprotective agents against Alzheimer's disease: rational design, synthesis evaluation, PPAR-γ binding assay and transactivation and expression studies.

Alzheimer's disease (AD) is a neurological disorder. It is caused by accumulation of amyloid beta (Aβ) plaques and tau tangles, which gradually leads to cognitive decline and memory loss. Peroxisome proliferator-activated receptor gamma (PPAR-γ), a nuclear receptor, plays a significant role in regulating genes responsible for metabolism and inflammation.