Publications by authors named "P Ortega Molina"
Adipose-derived stem cells (ADSCs) have an important role in the modulation of burned tissue repair through the release of paracrine factors that stimulate the wound healing response. In this study, we tested the hypothesis that smoking status alters the profile of paracrine factors secreted from ADSCs isolated from damaged adipose tissue. Adipose tissue was collected from adult patients (N=8) with severe burn injuries (>20% total body surface area) at the index operation.
View Article and Find Full Text PDFExcess dietary salt and salt-sensitivity contribute to cardiovascular disease. Distinct T cell phenotypic responses to high salt and hypertension as well as influences from environmental cues are not well understood. The aryl hydrocarbon receptor (AhR) is activated by dietary ligands, promoting T cell and systemic homeostasis.
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- Limited data exist in Chile about the quality of life for patients undergoing colorectal surgery, with existing surveys lacking thorough instructions and standardization.
- The FACT-C survey was validated by colorectal surgery experts in Chile, showing an excellent Content Validity Coefficient (CVC) above 0.9, indicating strong agreement on its effectiveness to measure quality of life.
- Minor adjustments were made for clarity, setting the stage for further validation in Chilean patients to ensure the survey's relevance and applicability.
Background: Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. Placenta-derived extracellular vesicles (EVs), necessary in maternal-fetal communication, might contribute to PE pathogenesis. Moreover, neutrophil extracellular traps (NETs) play a pathogenic role in other complement-mediated pathologies, and their contribution in PE remains unexplored.
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