Publications by authors named "P Omer Ali"
Upregulation of HSP90α in the lungs and circulation in sarcoidosis.
Front Med (Lausanne)
January 2025
Background: Sarcoidosis is a systemic granulomatous disease of unknown cause. Natural improvement with favorable outcome is common, but a significant number of patients present with difficult to manage and progressive disease. The identification of biomarkers associated with disease activity and progression is warranted.
View Article and Find Full Text PDFThe dual task cost of gait (DTC) is an accessible and cost-effective test that can help identify individuals with cognitive decline and dementia. However, its neural substrate has not been widely described. This study aims to investigate the neural substrate of the high DTC in older adults across the spectrum of cognitive decline.
View Article and Find Full Text PDFBackground: The evolving impact of climate change on adolescents' health is a pressing global concern. Climate change's effects on their physical, mental, and social well-being worsen unique developmental challenges for adolescents. This study aims to map existing evidence, identify gaps, and highlight research and intervention needs.
View Article and Find Full Text PDFArticle Synopsis
- Idiopathic pulmonary fibrosis (IPF) is a severe lung disease marked by excessive scarring, leading to poor respiratory function and a need for new treatment strategies, particularly involving macrophages, the key immune cells in the lungs.
- The study aimed to explore macrophage behavior in lung slices (PCLS), which are real lung tissues cultured in a lab, to better replicate the lung environment compared to isolated cells in vitro.
- Results showed that a polarization cocktail of specific cytokines can induce macrophage markers related to lung fibrosis in PCLS without harming the tissue, demonstrating a promising model for studying macrophage roles in IPF.