Publications by authors named "P Oleksy"

Article Synopsis
  • Biosimilars like MYL-1701P, a version of aflibercept, offer potentially cheaper options for treating diabetic macular edema (DME), but their efficacy and safety compared to the original have not been fully studied.
  • A randomized double-masked trial across multiple countries involved 355 participants with DME to compare MYL-1701P and aflibercept, focusing on vision improvement and side effects over a year.
  • Results showed similar improvements in visual acuity between the two treatments after 8 weeks, with MYL-1701P achieving an adjusted mean difference of just 0.04 letters from aflibercept, indicating comparable effectiveness.
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Introduction: SB11 (Byooviz™; Samsung Bioepis Co., Ltd.) is a ranibizumab (Lucentis; Genentech, Inc.

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Wireless capsule endoscopes take and send photos of the human digestive tract, which are used for medical diagnosis. The capsule's location enables exact identification of the regions with lesions. This can be carried out by analyzing the parameters of the electromagnetic wave received from the capsule.

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Purpose: This trial was conducted to investigate the clinical equivalence of the proposed biosimilar FYB201 and reference ranibizumab in patients with treatment-naive, subfoveal choroidal neovascularization caused by neovascular age-related macular degeneration (nAMD).

Design: This was a prospective, multicenter, evaluation-masked, parallel-group, 48-week, phase III randomized study.

Participants: A total of 477 patients were randomly assigned to receive FYB201 (n = 238) or reference ranibizumab (n = 239).

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Objectives: Maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) have a meaningful impact on pregnancy and perinatal outcomes. The first aim of the study was to analyze the association between pre-pregnancy BMI and the prevalence of small for gestational age (SGA) and large for gestational age (LGA) outcomes. The second aim was to assess the relation- ship between pre-pregnancy BMI combined with gestational weight gain (GWG) and the prevalence of SGA and LGA measurements.

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