Publications by authors named "P Okorie"

Article Synopsis
  • Signal transduction is key for communication and response in microbial communities, allowing them to adapt to environmental changes and establish structures for collective behaviors.
  • Microbial communication occurs through methods like quorum sensing, biofilm formation, and chemotaxis, which help coordinate activities, enhance resource use, and improve resilience against stress.
  • Understanding these signaling processes, especially in synthetic microbial consortia, has important implications for biotechnology, including biosensors, biodegradation, and waste management.
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Background: Pregnancy is a significant risk factor for Venous Thromboembolism (VTE) which results in high maternal and perinatal morbidity and mortality rates. Awareness creation is one of the preventable strategies of VTE. To this effect, we designed the 'Move for Flow' program aimed at maternal health education on VTE, its symptoms and preventive strategies.

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Hibiscus sabdariffa (HS) has gained attention as an anti-hypertensive agent. In the present study, we hypothesized that anthocyanins from HS may attenuate salt-induced hypertension in rats by suppressing the components of renin-angiotensin-aldoslestrone system (RAAS). Hypertension was induced in the rats by adding 8% NaCl in their diet for six weeks.

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Derangements of neuroimmune, neurotrophic and neurochemical homeostasis have important implications in psychosocial stress-induced psychopathologies. Whether quercetin, a neuroactive compound, protects against psychosocial stress-induced psychiatric disturbances particularly via neurochemical mechanisms remain less well elucidated. Therefore, we further investigated the putative neurochemical as well as other cellular mechanisms of quercetin on social-defeat stress (SDS) model of psychosocial impairments.

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Background: and soil transmitted helminth (STHs) infection are widespread in sub-Sahara Africa, where co-infection is also common. This study assessed the prevalence of these infections and their risk factors among pregnant women in Osogbo, Nigeria.

Methods: A total of 200 pregnant women attending the antenatal clinic were recruited.

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