Tumor markers (pregnancy protein 1, placental-specific tissue protein 10, placental-specific tissue protein 12, alpha1-fetoprotein) in patients with bronchial carcinoma.

The concentrations of pregnancy protein 1 (SP1), placental-specific tissue protein 10 (PP10), placental-specific tissue protein 12 (PP12) and alpha1-Fetoprotein (AFP) were analyzed in serum samples of 83 patients with bronchial carcinoma at stages II-IV Protein levels were determined by means of single radial immunodiffusion, rocket immuno-electrophoresis, radioimmunoassay and enzyme- immunoassay. PP12 and AFP serum concentrations were significantly increased in the cancer group compared with the control group. PP12 (control group: x=54.

[Determination of placental protein 12 (insulin-like growth factor binding protein 25) in pleural effusion of various origins].

It is reported on the possible role of the radioimmunological estimation of placental protein 12 (PP 12; insulin-like growth factor binding protein 25, IGF-BP 25) in pleural effusions of patients with lung cancer, with pleural carcinosis of extrathoracal carcinomas and benign pleural diseases, respectively. There are more PP 12, IGF-BP 25-positive cases at benign diseases than at carcinomas at all. It is discussed the possible importance of PP 12, IGF-BP 25 as a binding protein of growth factor s IGF-I and -II.

[Peak flow measurement].

Peak flow rate measurements with a simple device are useful in detecting and objective assessment of obstructive airway disease. They are easy to perform and offer a rational basis for antiobstructive treatment.

[Electronic spirometry].

Electronic spirometry on the basis of forced expiration and flow-volume-curve possess many advantages for the detection of ventilatory alterations in human lung.

[Results of nutrition diagnostic studies in patients with bronchial cancer].

A group of 71 patients with bronchial carcinomas are submitted to nutritional assessment in this trial. A 6-point valuation scan from Schmoz et al. for the nutritional assessment is used.