Center Volume Not Associated with Survival Benefit of Inter-hospital Transfer for Pediatric CardiacSurger.

Objective: To evaluate the relationship between center volume and inpatient mortality after inter-hospital transfer among patients undergoing pediatric cardiac surgery using contemporary real-world data.

Methods: The Kids' Inpatient Database (KID) was queried for cardiopulmonary bypass (CPB) cases (CPB) for years 2016 and 2019. Hospitals were divided into three groups based on terciles of volume: "low": ≤103 cases/year, "mid":104-194 cases/year, and "high": >194 cases/year.

Evaluation of the penetration capacity of bacteria through layers of different face mask types and wearing conditions.

The aim of this study was to quantify the number of non-airborne bacteria that can passively penetrate the layers of four mask types (surgical mask, community face mask type 1 (CFM1), biocidal CFM1 and CFM2) and to determine the influence of wearing conditions for the surgical type. A mask wearer simulator consisting of a 3D anatomical replica of the upper airway connected to a breathing pump was used. Wearing time, filtration quality of the mask, fit (loose vs.

Potential of training of anti- therapeutic phages against multidrug-resistant isolates is restricted by inter- and intra-sequence type specificity.

Phage therapy appears to be a promising approach to tackle multidrug-resistant bacteria, including staphylococci. However, most anti-staphylococcal phages have been characterized in , while a limited number of studies investigated phage activity against . We studied the potential of phage training to extend the host range of two types of anti-.

Vaccines and monoclonal antibodies to prevent healthcare-associated bacterial infections.

SUMMARYHealthcare-associated infections (HAIs) represent a burden for public health with a high prevalence and high death rates associated with them. Pathogens with a high potential for antimicrobial resistance, such as ESKAPE pathogens ( and ) and , are responsible for most HAIs. Despite the implementation of infection prevention and control intervention, globally, HAIs prevalence is stable and they are mainly due to endogenous pathogens.