Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis.

Yersinia pestis, the causative agent of plague, is a highly uniform clone that diverged recently from the enteric pathogen Yersinia pseudotuberculosis. Despite their close genetic relationship, they differ radically in their pathogenicity and transmission. Here, we report the complete genomic sequence of Y.

Quantitative chemical identification of four gases in remote infrared (9-11 mum) differential absorption lidar experiments.

A combined experimental and computational approach utilizing tunable CO(2) lasers and chemometric analysis was employed to detect chemicals and their concentrations in the field under controlled release conditions. We collected absorption spectra for four organic gases in the laboratory by lasing 40 lines of the laser in the 9.3-10.

Picosecond infrared study of the photodynamics of carbonmonoxy-cytochrome c oxidase.

Time-resolved infrared (TRIR) techniques have been employed to study the reactions of carbon monoxide with the cytochrome alpha 3-Cu(B) site of cytochrome c oxidase (CcO). The ligation dynamics immediately following photodissociation have been investigated using picosecond TRIR spectroscopy and linear dichroism. The rate of photoinitiated transfer of CO from cytochrome alpha 3 to CuB was measured directly by monitoring the development of the transient CuBCO absorption.

Ultrafast infrared spectroscopy.

Recent advances in ultrafast infrared spectroscopy are described, including experimental details and fundamental limitations. The utility of this technique is illustrated with two recent examples.