[The effect of hyperthyroidism on the cognition processes and the state of the glial intermediate filaments in the rat brain].

The effects of hyperthyreosis on oxidative stress, state of glial intermediate filaments and memory were investigated. We observed a significant increase in lipid peroxidation products into both hippocampus and cortex and memory worsening. The changes of GFAP polypeptides was observed in hippocampus and cortex.

[The changes of expression and Fc-gamma-receptor's polypeptide composition of fetal small intestine enterocytes in Bos primigenius taurus L].

The expression and polypeptide composition of Fc-gamma-receptors of enterocytes from Bos primigenius taurus L. intestine at 3-, 5-, 7-, 9- month of fetal development was investigated. The results of immunobloting show similar composition of Fc-gamma-receptors extracted from apical and basolateral membranes.

[Age-related characteristics of glial fibrillary acidic protein level in the rat brain structures in pain syndrome].

In experiments in white Wistar rats of three-age groups (immature, mature and old rats) content of glial fibrous acidic protein (GFAP) was investigated in cerebral cortex, hippocampus, thalamus and brain stem after the carrying out of laparotomy. The correlation between emotional activity and the level of GFAP has been found in the given structures of a brain. In immature animals, the activation of emotional component of behaviour was accompanied by decrease in polypeptide's soluble and insoluble fractions in brain stem by 16% and 18%, respectively (p<0.

[Effect of hypothyroidism on glial fibrillary acid protein in the structures of the rat brain].

The content and polypeptide composition of the glial fibrillary acid protein (GFAP) in the hemispheres' cortex, hippocamp, thalamus and brain stem in the condition of thyroid gland hypofunction in Wistar rats of different age (preadolescent rats five weeks old, pubertal rats five months old and old rats 18 - 20 months old) were investigated. Hypothyroidism was created by adding mercasolil (10 mg/kg) to the standard diet. At the end of experiment the level of thyrotropin and thyroxin in serum was defined with immunoenzyme method.

[Fatty-acidic content in the brain structures of hypothyroid rats of different age groups].

The content of fatty acids in the cerebral cortex and hippocampus was studied in an experiment on Wistar rats of the three age groups (5-weeks, puberal and old- 20-22 weeks) with an induced hypothyroidism (simulation was achieved by a 2 week prior supplement of L-thyroxin and final monitoring of thyroxin levels in serum). It was determined that the major variations of free fatty acids were noticed in the cerebral cortex and hippocampus among puberal rats, and somewhat lower shifts in premature (5 weeks) and old animals. The increase of free fatty acids in premature rats was registered in spectrum C17-C22.