Publications by authors named "P O Maksimchuk"

Nanoparticles (NPs) with reactive oxygen species (ROS)-regulating ability have recently attracted great attention as promising agents for nanomedicine. In the present study, we have analyzed the effects of TiOdefect structure related to the presence of stoichiometric (Ti) and non-stoichiometric (Tiand Ti) titanium ions in the crystal lattice and TiONPs aggregation ability on HO- and tert-butyl hydroperoxide (tBOOH)-induced ROS production in L929 cells. Synthesized TiO-A, TiO-B, and TiO-C NPs with varying Ti(Ti) content were characterized by x-ray powder diffraction, transmission electron microscopy, small-angle x-ray scattering, x-ray photoelectron spectroscopy, and optical spectroscopy methods.

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Unlabelled: Aim In the current study, hemocompatibility of three major commercially available types of carrageenans (ι, κ and λ) was investigated focusing on eryptosis.

Materials And Methods: Carrageenans of ι-, κ- and λ-types were incubated with washed erythrocytes (hematocrit 0.4%) at 0-1-5-10 g/L for either 24 h or 48 h.

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. Rare-earth orthovanadate nanoparticles (ReVO:Eu, Re = Gd, Y or La) are promising agents for photodynamic therapy of cancer due to their modifiable redox properties. However, their toxicity limits their application.

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Titanium dioxide (TiO) nanoparticles are promising biomedical agents characterized by good biocompatibility. In this study, we explored the cytotoxicity of TiO nanoparticles with a different Ti(Ti)/Ti ratio and analyzed the efficiency of eryptosis indices as a tool in nanotoxicology. Two types of TiO nanoparticles (NPs) were synthesized by the hydrolysis of titanium alkoxide varying the nitric acid content in the hydrolysis mixture.

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The search for novel antimicrobial agents is of huge importance. Nanomaterials can come to the rescue in this case. The aim of this study was to assess the cytotoxicity and antimicrobial effects of rare-earth-based orthovanadate nanoparticles.

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