Improving outcomes in carcinoid heart disease - learning from a single centre.

Introduction: A significant proportion of patients with carcinoid syndrome develop carcinoid heart disease (CHD). Valve degeneration can lead to right heart failure, and worsening prognosis. Replacement of affected valves is an effective therapy.

Correction to: Heart Valve Disease Awareness Survey 2017: what did we achieve since 2015?

The first and last names of all authors were interchanged in the original publication.

Heart Valve Disease Awareness Survey 2017: what did we achieve since 2015?

Aims: The 2015 Heart Valve Disease Awareness Survey showed a low knowledge and awareness about heart valve disease in the general population despite its high prevalence and morbidity. The 2017 survey was conducted to re-evaluate concern and knowledge about heart valve disease after 2 years of rapidly increasing patient numbers presenting with heart valve disease.

Methods And Results: A total of 12,820 people aged 60 years or older in 11 European countries took part in the survey.

Sugar-induced blood pressure elevations over the lifespan of three substrains of Wistar rats.

Objective: Since the majority of studies concerned with sugar-induced blood pressure elevation have principally been short-term, the present investigation followed the effects of heavy sucrose ingestion on systolic blood pressure (SBP) and related parameters over the lifespan of three substrains of Wistar rats.

Methods: Two hundred twenty-five rats (75 spontaneously hypertensive rats (SHR), 75 Wistar Kyoto rats (WKY), 75 Munich Wistar rats (WAM) were given one of five diets. The baseline diet in terms of calories derived 32% from sucrose, 33% from protein, and 35% from fat.

Hepatitis B vaccine booster dose: low-dose recombinant hepatitis B vaccines as a booster dose.

Background: The timing and best regimen for a booster dose of hepatitis B vaccine have not been determined.

Methods: Two studies were conducted to determine the response to a booster dose of 5 micrograms recombinant hepatitis B vaccine. In the first study, a 5 micrograms (0.