The indices of collagen metabolism (free, peptide- and protein bound hydroxyproline) as well as blood plasma proteolytic activity were studied in repeated immobilization (up to 5 days) and skin electropuncture (up to 8 days) in rats. Repeated immobilization (strong stress) steadily increased the contents of free oxyproline and induced undulating changes in the level of other indices under study. Electropuncture (slight stress) produced a short-term increase in free oxyproline blood plasma level.
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