Publications by authors named "P N Meissner"
A minority of American youth meet CDC lifestyle behavior recommendations. Children in the Bronx face barriers to healthy behaviors amplified by COVID-19. This research evaluated baseline behavior among distinct cohorts attending afterschool programming before and after the COVID-19 shutdown.
View Article and Find Full Text PDFThe detection of founder pathogenic variants, those observed in high frequency only in a group of individuals with increased inter-relatedness, can help improve delivery of health care for that community. We identified 16 groups with shared ancestry, based on genomic segments that are shared through identity by descent (IBD), in New York City using the genomic data of 25,366 residents from the All Of Us Research Program and the Mount Sinai Bio biobank. From these groups we defined 8 as founder populations, mostly communities currently under-represented in medical genomics research, such as Puerto Rican, Garifuna and Filipino/Pacific Islanders.
View Article and Find Full Text PDFPurpose: We undertook a trial to test the efficacy of a technology-assisted health coaching intervention for weight management, called Goals for Eating and Moving (GEM), within primary care.
Methods: This cluster-randomized controlled trial enrolled 19 primary care teams with 63 clinicians; 9 teams were randomized to GEM and 10 to enhanced usual care (EUC). The GEM intervention included 1 in-person and up to 12 telephone-delivered coaching sessions.
Importance: Hepatitis C virus (HCV) reinfection after curative treatment remains a concern for people who inject drugs.
Objective: To assess the incidence of HCV reinfection and associated risk factors.
Design, Setting, And Participants: This cohort study is a secondary analysis of a randomized clinical trial that was conducted across opioid treatment programs and community health centers in the US between September 2016 and August 2018.
Article Synopsis
- The acute hepatic porphyrias (AHPs) are a group of four rare genetic disorders that cause serious, episodic neurological symptoms due to a buildup of specific chemical precursors in the liver.
- Diagnosis can be challenging due to non-specific symptoms, but specialized tests during attacks can confirm the condition.
- Treatment for severe episodes includes intravenous hemin, and potential long-term management with givosiran is available for patients with frequent attacks; regular health surveillance is also necessary to monitor for serious complications.